GAT3 Antibody [Janelia Fluor® 635] Summary
| Immunogen | Produced in rabbits immunized with E. coli-derived Human GAT3 fragment. |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Rabbit |
| Gene | SLC6A11 |
| Purity | Antigen and protein A Affinity-purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward |
Applications/Dilutions
| Dilutions |
|
| Application Notes | Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
| Storage | Store at 4C in the dark. |
| Buffer | 50mM Sodium Borate |
| Preservative | 0.05% Sodium Azide |
| Purity | Antigen and protein A Affinity-purified |
Notes
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
Alternate Names for GAT3 Antibody [Janelia Fluor® 635]
- GABA Transporter 3
- GABT3
- GAT-3
- GAT3sodium- and chloride-dependent GABA transporter 3
- GAT4
- solute carrier family 6 (neurotransmitter transporter, GABA), member 11
- Solute carrier family 6 member 11
Background
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl negative channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-3 has been found to be localized to astrocytes within the cerebral cortex indicating that this transporter mediates GABA uptake into glial cells (Minelli et al., 1996).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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- Immunohistochemistry-Paraffin
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